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Diabetic nephropathy will be genetic?

2017-02-06 14:59

Have a genetic cause of diabetic nephropathy? For diabetic nephropathy is genetic research will not stop, many scholars have found that the evidence pointing in the same direction, genetic factors play a crucial role in the pathogenesis of diabetic nephropathy. But only to a certain extent increased susceptibility to diabetic nephropathy. Genetics may be the cause of diabetic nephropathy, but it is not the only determinant.

1, the incidence of diabetic nephropathy has a high familial aggregation.

2. Diabetic nephropathy is closely related to familial hypertension and cardiovascular disease

3, diabetic nephropathy in the presence of racial differences

4. There is more evidence to show that the sodium ion lithium ion exchange and leucocyte sodium hydrogen ion exchange in erythrocytes of type 1 diabetic patients with diabetic nephropathy were significantly increased.

To see this, maybe a lot of people to do genetic diabetic nephropathy is given a definite answer, but must say that although both the diabetic nephropathy in patients with type 1 diabetes or type 2 diabetes patients will have a complication of diabetes, is also common, but is not to say that all patients with diabetes in diabetic nephropathy who, although genetic factors may also be the cause of diabetic nephropathy, but only determines the increased susceptibility of diabetic nephropathy, and the common genetic diseases are essentially different, the former is due to many factors, such as environmental factors, and can not accurately calculate the genetic probability, the latter can be.

However, it cannot be denied that diabetic nephropathy with genetic color, some think that at present, in diabetic nephropathy related pathogenic gene is ACE gene, aldose reductase gene, insulin receptor gene, type IV collagen genes, but also show some results for the study of family, DN will not impossible, because the results of the study the survey found that type 2 diabetes with diabetic nephropathy may be associated with certain genes on the chromosomes.
But also need to see the harm of diabetic nephropathy, because the disease is a major cause of end-stage renal failure, will cause death, therefore, diabetic nephropathy will do the genetic even knowing the answer, should be prevented, because not all patients with diabetes will develop diabetic nephropathy.

For diabetic nephropathy in this disease, genetic response in patients with diabetic nephropathy: right, as can be seen from the above, although genetic may be one of the causes of diabetic nephropathy, but the genetic and hereditary nephropathy that unlike the color with the color of genetic, usually pathogenicity gene only increased the probability of occurrence of diabetic nephropathy.

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