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What is a nephrotic syndrome?

2017-01-24 14:56

 

Nephrotic syndrome is caused by a variety of causes of gl.omerular basement membrane disease, which is a syndrome of renal glomerular disease. The significant increase of plasma protein permeability was characterized by glomerular filtration. Inflammation with or without a glomerulus. Proteinuria, CAST, renal function decreased. What are the clinical manifestations of nephrotic syndrome? Answer: with systemic edema, severe proteinuria ( ≥ 3.5 g / 24 hours ), hyperlipidemia, Low is the main manifestation. ( 1 ) edema: partly due to the decrease of jiaoshenya, the capillary still pressure of the capillary more than jiaoshenya, the liquid enters the tissue, secondary effective blood volume reduced; The latter can increase the retention of sodium by compensatory mechanism, but the blood volume of 50 % patients is normal or increased, plasma renin is at low level, suggesting that the nephrotic syndrome may be related to the primary renal. The edema mechanism of the disease may be multifactorial, in different pathological types, different stages or different degrees of nephrotic syndrome, may have different mechanisms or mechanisms to participate in, and the sodium water regulation dysfunction may be the main cause of edema. ( 2 ) a large number of proteinuria: proteinuria in fixed range generally indicates diffuse glomerular disease. ⑶ hyperlipidemia: the hyperlipidemia of nephrotic syndrome is inversely proportional to the amount of protein. The serum total cholesterol, free cholesterol and Zhijun increased. Glycerol sanzhiyiban increased in the presence of obvious. Plasma very low density lipoprotein ( density ), low density lipoprotein ( LDL ) and lipoprotein may increase early, but in severe cases.

 

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