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How to choose antidiabetic drugs in patients with diabetic nephropathy

2017-01-24 15:16
How to choose antidiabetic drugs in patients with diabetic nephropathy
Diabetic nephropathy is one of the most important complications in patients with diabetes mellitus. Because of its complex metabolic disorder, once developed to end-stage renal disease, often more difficult than the treatment of other kidney diseases. The pathogenesis of diabetic nephropathy is not clear. At present, many factors are involved. Diabetic nephropathy is a systemic microvascular disease, and one of the disease, so the occurrence of diabetic nephropathy, microangiopathy is not often combined with other organs or systems, such as diabetic retinopathy and peripheral neuropathy.
How to choose antidiabetic drugs in patients with diabetic nephropathy
Steps / methods:
1 first, diabetic nephropathy patients to prevent hypoglycemia. Hypoglycemia is often used in patients with diabetic nephropathy hypoglycemic phenomenon, the clinical manifestations of hypoglycemia is hunger, dizziness, weakness, weakness, palpitations, irritability, and even coma, more harm to patients. Patients, when going out should carry, candy, fruit juice and other sugar content in order to prepare for timely consumption.
First step
2 the second is that we should actively treat insulin allergy, although the phenomenon of insulin allergy is relatively small, but it should also pay attention to. The clinical manifestations of insulin allergy to local skin rash itching, gastrointestinal reaction and so on, if there is an allergic reaction, on the body more harm, should immediately use antihistamines and corticosteroids or desensitization therapy.
3 the third is diabetic nephropathy patients, should be regularly replaced insulin injection site. In patients with diabetic nephropathy due to malnutrition, often associated with fat, in a part of the new long-term injection of insulin, will cause the injection site, subcutaneous fat atrophy or hypertrophy, therefore, should be regularly replace the injection site, not in the same part of continuous injection.
Matters needing attention:
Diabetic nephropathy patients, if the renal function is not good, for the class of hypoglycemic drugs can not be used, and its production of lactic acid, can not be discharged through the kidneys, so harmful to the human body. Sugar can be selected. Patients with diabetic nephropathy, in the choice of hypoglycemic drugs, we should try to choose a number of drugs excreted through the kidneys.

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