What is the cause of acute nephritis?2017-05-03 14:59
Acute nephritis is a group of rapid progression of the disease, hematuria, proteinuria, edema and hypertension were the main clinical manifestations, and the rapid development of general oliguria, anuria and prognosis of renal failure in severe glomerulonephritis. What is the cause of rapidly progressive nephritis patients is concerned?. The following analysis of the etiology of progressive glomerulonephritis.
The etiology of the disease is divided into two categories: primary and secondary:
(1) primary: the cause of the disease is unknown, there may be a history of streptococcal infection or gastrointestinal tract, respiratory tract infection.
It can be divided into three types according to its pathogenesis:
Type I anti glomerular basement membrane anti body type, this type of blood in patients with anti basement membrane antibody positive, under the electron microscope can be seen in the basement membrane of the inner line of sediment.
Type five is an immune complex, and a mass of immune complex deposition on the basement membrane was observed under electron microscope.
The pathogenesis of dish type is unknown, and there is no immune complex deposition in glomeruli. Type three is the most dangerous and the most difficult to treat.
(2) secondary: may be secondary to the following situations.
Secondary primary glomerular disease. Such as mesangial proliferative glomerulonephritis, membranous nephropathy, IgA nephropathy (rare), etc..
Secondary to infectious diseases: such as infective endocarditis, streptococcus infection after nephritis, hidden organ bacterial lesions, hepatitis B and influenza.
The secondary to other diseases such as systemic lupus erythematosus, systemic vasculitis, pulmonary hemorrhage in a nephritic syndrome, allergic purpura, idiopathic cryoglobulinemia, malignant tumor and relapsing polychondritis.
The above analysis is to explain the radical cause of nephritis, hope that patients can understand, according to the cause of symptomatic treatment.