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The etiology of primary acute nephritis

2017-03-16 10:51

Secondary to other primary glomerulonephritis, mesangial proliferative glomerulonephritis (especially type II), membranous glomerulonephritis with additional basement membrane nephritis, IgA nephritis (less).

 

The following diseases cause the rapidly progressive glomerulonephritis .

 

Primary glomerular disease

 

1 primary diffuse crescentic glomerulonephritis

 

(1) type I: IgG linear deposition (anti glomerular basement membrane antibody mediated).

 

(2) type II: IgG particle deposition (immune complex mediated).

 

(3) type III: deposition with little or no Ig (lack of immune response).

 

(4) anti neutrophil cytoplasmic antibody (ANCA) - induced (vasculitis).

 

2 secondary to other primary glomerulonephritis: mesangial proliferative glomerulonephritis (especially type II), membranous glomerulonephritis with additional basement membrane nephritis, IgA nephritis (Shao Jian).

 

Associated with infectious diseases 

 

Acute streptococcal infection, acute or subacute infective endocarditis, chronic sepsis caused by visceral suppurative lesions and glomerulonephritis.

 

Other infections: shunt nephritis, hepatitis B virus nephritis, human immunodeficiency virus infection.

 

With multi system disease

 

Systemic lupus marks sores, Goodpasture syndrome, allergic purpura, diffuse vasculitis such as necrotizing granuloma, allergic vasculitis and other types of mixed cryoglobulinemia, rheumatoid arthritis, vasculitis associated with malignant tumor and relapsing polychondritis.

 

Drugs

 

Penicillamine, hydralazine, allopurinol and rifampin.

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