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How does the patient of hypertensive kidney function choose medication to treat?

2017-05-03 16:07

Hypertensive renal insufficiency patients how to choose the treatment of hypertension complicated with nephropathy? Once, it will continue to worsen the condition of hypertensive nephropathy progress, eventually developed into renal insufficiency, hypertension and uremia hypertension. At this time, for patients with hypertensive nephropathy, the rational use of drugs can effectively control the condition of hypertensive nephropathy, delay the progression of renal disease. How does the patient of hypertensive kidney function choose medication to treat?

First, antihypertensive drugs that do not affect renal function should be selected. Nicardipine and nifedipine two dihydropyridine calcium antagonist, mainly metabolized in the liver, and to maintain renal blood flow, maintain kidney function and has good effect, therefore, associated with renal dysfunction in hypertension, using two dihydropyridine calcium antagonist, can be used according to the normal dose, no reduction. Beta blockers should be reduced in patients with severe renal dysfunction. Angiotensin converting enzyme inhibitors have a protective effect on the kidneys, but also can reduce proteinuria, but creatinine clearance test every minute below 10ml in renal dysfunction, should be reduced as appropriate. Alpha blockers should also be reduced when renal function is impaired.

Secondly, the diastolic pressure is generally controlled at 12.0kPa (90mmHg). The steady state of low pressure will play a role in alleviating the renal ischemia and hypoxia, which may help to delay the deterioration of renal function in patients with hypertension.

Finally, the rational use of antihypertensive diuretic. Antihypertensive diuretic such as hydrochlorothiazide, often as the drug of choice. Potassium sparing diuretics triamterene, such as spironolactone, because it can cause hypertension, renal insufficiency, people should be careful. Furosemide, ethacrynic acid had severe impairment associated with uremia, oliguria, anuria patients can try in renal function.

Of course, for patients with hypertensive nephropathy, the choice of clinical medication should not only be able to control blood pressure, so that it is maintained at a stable level, but also affect renal function. But these measures are only a temporary relief of symptoms of hypertension in patients with kidney disease, temporary control of the role of the disease, and the role of the real treatment of the damage to the kidney is not reflected. That alone is difficult to achieve effective single drug therapy for patients with hypertensive nephropathy, especially has entered into the stage of renal function insufficiency hypertension nephropathy patients, and then as soon as the lesion of the kidney to take effective treatment measures, the decline in renal function in patients with hypertension will continue to occur, eventually because of the loss of function and lead to adverse consequences. If you or your loved ones suffering from high blood pressure disease, do a good job on a regular basis to check the work; if already suffering from high blood pressure kidney disease, hope to be able to regulate the treatment as soon as possible, to prevent deterioration of the disease, delay.

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