Proteinuria is closely related to the human kidney2017-09-22 17:53
Albuminuria is one of the most common symptoms of chronic kidney disease. In general, proteinuria, neither pain nor itching, and generally will not bring great inconvenience to life. But if it is not cured for a long time, it will bring serious consequences to the patient.
First of all, there are two main types of proteinuria in chronic kidney disease: one is glomerular proteinuria, and the other is tubular proteinuria. Under normal circumstances, the blood flowing through the glomerulus, blood protein because of its size and charge properties, most will not leak into the renal tubule, a small amount of leakage into the renal tubule protein, most will be tubular reabsorption back to the blood circulation and excreted in the urine left, general 24 hours is not more than 150mg. Healthy adolescents are slightly higher, but generally not more than 250mg/24 hours.
Chronic kidney disease, glomerular proteinuria is because the glomerular filtration barrier damage, said the more specific is the glomerular intrinsic cells or stromal damage, causing them to maintain renal glomerular filtration function is impaired, so there will be a lot of beyond the normal range, was not out to leak leakage protein in the renal tubule, more than renal tubular reabsorption, many protein excreted in the urine, resulting in the formation of glomerular proteinuria. The tubular proteinuria appeared because of renal tubular epithelial cell damage, resulting in the re absorption function damaged, unable to re absorption of the urine protein, can also cause some protein excreted, so that the formation of tubular proteinuria. In general, proteinuria is 24 times higher in renal tubular proteinuria than in renal tubular proteinuria.
From the above we can see that both glomerular proteinuria and renal tubular proteinuria are related to the health of renal cells in patients, thus affecting proteinuria.