How does the three common kidney disease occur?2017-12-11 17:21
Small lesions (children): the disease is common in children, and some of the elderly also appear, but young and middle-aged are rare. The disease is sensitive to the hormone, and the index of urine protein is fast and easy to relapse.
The causes of disease: intrusion causes lesions mainly lies in the outside of virus and bacteria, the immune system into the human body will activate the body and release of vascular permeability factor, it will make the capillary of kidney damage, the protein will pass through blood vessels, into the urine, proteinuria, and renal lesions.
The immune ability of children and middle aged and old people is relatively low, and it is more likely to cause renal capillary damage and cause kidney disease.
IgA nephropathy: most of the nephropathy is mostly young people. It is also one of the most common chronic glomerulonephritis. It basically occupies 50% of the primary chronic glomerulonephritis group.
The cause of the disease: IGA nephropathy is similar to the root of small lesions, which are closely related to the invasion of external pathogens. Once the body is invaded by bacteria and viruses, all kinds of infection will happen, resulting in a harmful substance called "polymer IgA1", and then another harmful substance will emerge: complement IgG.
The two substances, which precipitate in the kidney for a long time, cause blood cells to leak out. The clinical manifestation of hematuria or microscopic hematuria can be accompanied by different levels of proteinuria. This is also the most basic feature of clinical IGA nephropathy.
Membranous nephropathy: membranous nephropathy is often seen in middle-aged people. Hormone and immunosuppressive agents are commonly used, and the treatment cycle is longer.
Causes: the main cause of membranous nephropathy is the intake of carbohydrate, fat, protein and other nutrient rich too much, and middle-aged body prone to heavy metal exceed the standard, which will lead to the body of a normal substance called phospholipase A2 receptor appears a conformational change, abnormal formation of phospholipase A2 receptor.
The abnormal phospholipase A2 receptor is the leading cause of membranous nephropathy. Once it enters the kidney, it will destroy the normal structure of the kidneys and cause kidney disease.