Kidney syndrome and nephritis,which is more difficult to treat?2018-05-21 17:22
It is generally believed that the nephritis is mainly of protein, but it is not accurate. In fact, all kidney diseases can be referred to as "nephritis," because kidney pathology is mostly associated with inflammatory reactions. However, in the daily narrative, "nephritis" is usually referred to as the stage of the inflammatory response of the kidney disease, that is, before the blood creatinine is elevated.
Among them, all of the pathological types that show a large amount of urinary protein (urine protein greater than or equal to 3.5g/24h) and hypoalbuminemia (plasma albumin < 30g/l) are all "nephrotic syndrome". Therefore, nephrotic syndrome is a special category of nephritis, but we usually for the sake of convenience, it is more likely to be "nephritis" as "urine occult blood nephropathy."
In accordance with the above general understanding, the two sides have the following focuses in terms of treatment:
Nephritis. Since it is an inflammatory phase of nephropathy, the focus of treatment is on anti-inflammatory, but due to urinary occult blood in nephritis, most of them are glomerular capillary fissures caused by the proliferation of mesangial cells, so they are often treated conservatively or even alone. Patients with occult urine do not prescribe drugs but only observe them regularly.
Nephrotic syndrome. The treatment of nephrotic syndrome is mainly to eliminate urinary protein, and the vast majority of urinary protein production is caused by glomerular filtration barrier damage caused by inflammation, so the hormones that can inhibit the inflammatory response become routine medications. In addition to the addition of plasma albumin and the elimination of edema, it is the basic treatment of kidney.
From the human body's point of view, kidney damage is related to abnormal blood. Because the kidney is the most important blood purifying organ in the body, it can have an effect on the kidneys, whether it's blood or blood pressure. The current treatment regimen for conventional renal disease is still based on the suppression or elimination of symptoms, and the evaluation of the therapeutic effect is based on the change of symptoms.
However, from the point of view of blood changes, it can be imagined that future treatment regimens for blood purification should take more and more weight in the treatment of kidney disease, especially the phase of prevention and recovery of kidney disease.