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Manifestation and treatment of nephrotic syndrome with Chine

2017-06-08 09:15

Nephrotic syndrome is a group of symptoms characterized by a variety of causes, characterized by massive proteinuria, hypoproteinemia, edema, and hyperlipidemia, and is a common kidney disease. Nephrotic syndrome is more common in infants and young children, but also in all age groups. It is divided into two major groups, primary and secondary. The etiology of primary nephrotic syndrome is unknown, and some patients often have atypical history of upper respiratory tract infection. Secondary nephrotic syndrome has many causes, such as diabetes, systemic lupus erythematosus, tumor, drug, infection and so on.

Specific manifestations of nephrotic syndrome

1, proteinuria, proteinuria are the most basic features of nephrotic syndrome. A lot of albuminuria is a personal boundary. At present, my country is more than 3.5 grams / liter, most of the foreign countries for 3.5 grams / (1.73 cubic meters 24 hours).

2. The degree of hypoproteinemia is significantly related to the degree of albuminuria, generally <30 g / dl.

3, the most important risk of hyperlipidemia and hyperlipidemia is cardiovascular disease. The high risk status depends on whether the presence of hyperlipidemia persists and the level of protective lipoproteins in the blood.

4, edema in the face, legs and scrotum most obvious, and even pleural effusion, ascites.

In addition, there may be elevated blood pressure, varying degrees of renal dysfunction and more red blood cells in the urine.

Treatment of nephrotic syndrome with Chinese Medicine

TCM treatment of nephrotic syndrome should begin with 3 aspects: plug flow, clear source and double copy.

(1) plug flow mainly refers to the elimination or reduction of urinary protein loss. The commonly used drugs are compound Lei Gongteng syrup, which is composed of two layers of root, heart, xylem, Salvia miltiorrhiza and liquorice produced by Lei Gongteng.

(2) the main pointer of the Qing Dynasty adopted the syndrome differentiation and treatment measures to the cause of disease and pathogenesis, so as to clear the source. The prescriptions of different syndromes are as follows:

The kidney deficiency Astragalus, Codonopsis, Fang yam, Atractylodes, epimedium, mulberry, barley.

The deficiency of spleen and Kidney Yang Fang, cassia twig, attached to the peony, Atractylodes, Poria, Alisma, ginger, pig skin, areca Chen Hulu shell.

The liver and kidney yin deficiency. Dried rehmannia root, Ligustrum lucidum, medlar, Anemarrhena, Eclipta, Poria, Alisma; motherwort.

The kidney collateral obstruction party Shengdihuang, angelica, radix paeoniae rubra, Rhizoma Chuanxiong, peach kernel, safflower, epimedium, Hirudo powder (swallow).

The side of Phytolacca acinosa, Rhizoma alismatis, damp heat swollen red bean, eyes, skin, etc. areca Poria, notopterygium, rhubarb.

The wind cold and wind heat cold side with ephedra, Bai Xingren, Poria, tangerine peel, Pericarpium Arecae, mulberry bark, ginger clothing, Plantago herb, ephedra, gypsum with heat, forsythia, cogongrass rhizome, Radix Scutellariae, red bean, Houttuynia, Platycodon grandiflorum.

(3) a copy of the original protein mainly refers to the loss and disease causes. Haoshang blood fine compensation measures, including food and medicine. Medicine available black soybean pill: black soybean, astragalus, Atractylodes, Chinese yam, and use ejiao.

Prognosis of nephrotic syndrome

The prognosis of this disease is better. The patients with chronic kidney disease can be relieved by 1/4, and most of them respond well to corticosteroids and other drugs. But focal and segmental glomerulosclerosis and mesangial proliferative glomerulonephritis do not respond well to corticosteroids and immunosuppressive agents. The disease is easy to relapse, may be related to infection, fatigue and other incentives, because there is no effective measures to prevent recurrence, it should be long-term follow-up observation. For those who are not sensitive to recurrent or glucocorticoid, some patients can be relieved by the combination of Chinese medicine and Western medicine. A few cases were delayed and developed chronic renal failure. In view of the disease prognosis and pathological type, so patients with nephrotic syndrome, renal biopsy should be done as early as possible, to provide the basis for treatment.

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