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What tests should be made to suspect nephrotic syndrome?

2017-06-08 09:24

(1) in the case of suspected nephrotic syndrome, the usual examination is for the purpose of definite diagnosis:

Urine routine examination: urine protein qualitative and urine sediment microscopic examination can be used to determine if there is glomerular lesion.

24 hours urine protein quantification: nephrotic syndrome patients 24 hours urine protein quantitative more than 3.5G is a necessary condition for diagnosis.

Determination of plasma protein: nephrotic syndrome, plasma albumin lower than 30g is a prerequisite for diagnosis.

Blood lipid determination: nephrotic syndrome patients often have lipid metabolism disorder, blood lipids rise.

(2) in order to understand whether the renal function is impaired or damaged in nephrotic syndrome, we should further clarify the diagnosis and differential diagnosis, guide the formulation of treatment plans, estimate the prognosis, and make the following examinations according to the specific conditions:

Renal function tests: the frequent items are urea nitrogen (BUN) and creatinine (Scr), which is one of the frequently used items for understanding the impairment of renal function and its extent.

Electrolyte and CO2 binding force (CO2-CP) determination: used to understand whether there is electrolyte disturbance and acid-base imbalance, so as to correct in time.

Blood rheology examination: the blood of patients with nephrotic syndrome is often in hypercoagulable state, and the blood viscosity increases. This examination will help to understand the situation.

Fourth, check the following items can be selected according to need: serum complement, serum immunoglobulin, selective proteinuria index, urine protein polyacrylamide gel electrophoresis, urinary C3 and fibrin degradation products (FDP), anti renal antibody urine enzyme, serum and renal biopsy.

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